1. The age factor in optic nerve regeneration: Intrinsic and extrinsic barriers hinder successful recovery in the short-living killifish. Vanhunsel S, Bergmans S, Beckers A, Etienne I, Van Bergen T, De Groef L, Moons L. Aging Cell. 2022 Jan;21(1):e13537. doi: 10.1111/acel.13537. Epub 2021 Dec 19. PMID: 34927348 Free PMC article.
2. Common pathways in dementia and diabetic retinopathy: understanding the mechanisms of diabetes-related cognitive decline. Little K, Llorián-Salvador M, Scullion S, Hernández C, Simó-Servat O, Del Marco A, Bosma E, Vargas-Soria M, Carranza-Naval MJ, Van Bergen T, Galbiati S, Viganò I, Musi CA, Schlingemann R, Feyen J, Borsello T, Zerbini G, Klaassen I, Garcia-Alloza M, Simó R, Stitt AW; RECOGNISED consortium (GA 847749).Trends Endocrinol Metab. 2022 Jan;33(1):50-71. doi: 10.1016/j.tem.2021.10.008. Epub 2021 Nov 15. PMID: 34794851 Review.
3. Targeting Plasma Kallikrein With a Novel Bicyclic Peptide Inhibitor (THR-149) Reduces Retinal Thickening in a Diabetic Rat Model. Van Bergen T, Hu TT, Little K, De Groef L, Moons L, Stitt AW, Vermassen E, Feyen JHM. Invest Ophthalmol Vis Sci. 2021 Oct 4;62(13):18. doi: 10.1167/iovs.62.13.18. PMID: 34677569 Free PMC article.
4. Systemic exposure following intravitreal administration of therapeutic agents: an integrated pharmacokinetic approach. 1. THR-149. Vanhove M, Noppen B, Wagner JM, Van Bergen T, Barbeaux P, Stitt AW. J Pharmacokinet Pharmacodyn. 2021 Dec;48(6):825-836. doi: 10.1007/s10928-021-09773-w. Epub 2021 Jul 23. PMID: 34302260 Free PMC article.
5. IL-33trap-mediated IL-33 neutralization does not exacerbate choroidal neovascularization, but fails to protect against retinal degeneration in a dry age-related macular degeneration model. Van Hove I, Van Bergen T, Etienne I, Holgado A, Afonina IS, Beyaert R, Feyen JH, Hu TT. Exp Eye Res. 2021 Jun;207:108608. doi: 10.1016/j.exer.2021.108608. Epub 2021 Apr 27. PMID: 33930400
6. Targeting RGD-binding integrins as an integrative therapy for diabetic retinopathy and neovascular age-related macular degeneration. Van Hove I, Hu TT, Beets K, Van Bergen T, Etienne I, Stitt AW, Vermassen E, Feyen JHM. Prog Retin Eye Res. 2021 Nov;85:100966. doi: 10.1016/j.preteyeres.2021.100966. Epub 2021 Mar 26. PMID: 33775825 Review.
7. Heparanase Deficiency Is Associated with Disruption, Detachment, and Folding of the Retinal Pigment Epithelium. Van Bergen T, Etienne I, Jia J, Li JP, Vlodavsky I, Stitt A, Vermassen E, Feyen JHM. Curr Eye Res. 2021 Aug;46(8):1166-1170. doi: 10.1080/02713683.2020.1862239. Epub 2020 Dec 29. PMID: 33372561
8. Single-cell transcriptome analysis of the Akimba mouse retina reveals cell-type-specific insights into the pathobiology of diabetic retinopathy. Van Hove I, De Groef L, Boeckx B, Modave E, Hu TT, Beets K, Etienne I, Van Bergen T, Lambrechts D, Moons L, Feyen JHM, Porcu M. Diabetologia. 2020 Oct;63(10):2235-2248. doi: 10.1007/s00125-020-05218-0. Epub 2020 Jul 30. PMID: 32734440
9. Tightening the retinal glia limitans attenuates neuroinflammation after optic nerve injury. Lefevere E, Salinas-Navarro M, Andries L, Noterdaeme L, Etienne I, Van Wonterghem E, Vinckier S, Davis BM, Van Bergen T, Van Hove I, Movahedi K, Vandenbroucke RE, Moons L, De Groef L. Glia. 2020 Dec;68(12):2643-2660. doi: 10.1002/glia.23875. Epub 2020 Jul 9. PMID: 32645232
10. Single-Cell RNA Sequencing Maps Endothelial Metabolic Plasticity in Pathological Angiogenesis. Rohlenova K, Goveia J, García-Caballero M, Subramanian A, Kalucka J, Treps L, Falkenberg KD, de Rooij LPMH, Zheng Y, Lin L, Sokol L, Teuwen LA, Geldhof V, Taverna F, Pircher A, Conradi LC, Khan S, Stegen S, Panovska D, De Smet F, Staal FJT, Mclaughlin RJ, Vinckier S, Van Bergen T, Ectors N, De Haes P, Wang J, Bolund L, Schoonjans L, Karakach TK, Yang H, Carmeliet G, Liu Y, Thienpont B, Dewerchin M, Eelen G, Li X, Luo Y, Carmeliet P. Cell Metab. 2020 Apr 7;31(4):862-877.e14. doi: 10.1016/j.cmet.2020.03.009. PMID: 32268117
11. The Placental Growth Factor Pathway and Its Potential Role in Macular Degenerative Disease. Cunningham F, Van Bergen T, Canning P, Lengyel I, Feyen JHM, Stitt AW. Curr Eye Res. 2019 Aug;44(8):813-822. doi: 10.1080/02713683.2019.1614197. Epub 2019 May 24. PMID: 31055948 Review.
12. Longitudinal In Vivo Characterization of the Streptozotocin-Induced Diabetic Mouse Model: Focus on Early Inner Retinal Responses. Sergeys J, Etienne I, Van Hove I, Lefevere E, Stalmans I, Feyen JHM, Moons L, Van Bergen T. Invest Ophthalmol Vis Sci. 2019 Feb 1;60(2):807-822. doi: 10.1167/iovs.18-25372. PMID: 30811545
13. The potent small molecule integrin antagonist THR-687 is a promising next-generation therapy for retinal vascular disorders. Hu TT, Vanhove M, Porcu M, Van Hove I, Van Bergen T, Jonckx B, Barbeaux P, Vermassen E, Feyen JHM. Exp Eye Res. 2019 Mar;180:43-52. doi: 10.1016/j.exer.2018.11.022. Epub 2018 Nov 22. PMID: 30472075
14. The role of placental growth factor (PlGF) and its receptor system in retinal vascular diseases. Van Bergen T, Etienne I, Cunningham F, Moons L, Schlingemann RO, Feyen JHM, Stitt AW. Prog Retin Eye Res. 2019 Mar;69:116-136. doi: 10.1016/j.preteyeres.2018.10.006. Epub 2018 Oct 30. PMID: 30385175 Review.
15. Stable and Long-Lasting, Novel Bicyclic Peptide Plasma Kallikrein Inhibitors for the Treatment of Diabetic Macular Edema. Teufel DP, Bennett G, Harrison H, van Rietschoten K, Pavan S, Stace C, Le Floch F, Van Bergen T, Vermassen E, Barbeaux P, Hu TT, Feyen JHM, Vanhove M. J Med Chem. 2018 Apr 12;61(7):2823-2836. doi: 10.1021/acs.jmedchem.7b01625. Epub 2018 Mar 15. PMID: 29517911
16. Neutralization of placental growth factor as a novel treatment option in diabetic retinopathy. Van Bergen T, Hu TT, Etienne I, Reyns GE, Moons L, Feyen JHM. Exp Eye Res. 2017 Dec;165:136-150. doi: 10.1016/j.exer.2017.09.012. Epub 2017 Sep 28. PMID: 28965804
17. Integrin α5β1 Inhibition by CLT-28643 Reduces Postoperative Wound Healing in a Mouse Model of Glaucoma Filtration Surgery. Van Bergen T, Zahn G, Caldirola P, Fsadni M, Caram-Lelham N, Vandewalle E, Moons L, Stalmans I. Invest Ophthalmol Vis Sci. 2016 Nov 1;57(14):6428-6439. doi: 10.1167/iovs.16-19751. PMID: 27893886
18. The Combination of PlGF Inhibition and MMC as a Novel Anti-Scarring Strategy for Glaucoma Filtration Surgery. Van Bergen T, Jonckx B, Moons L, Feyen JH, Stalmans I. Invest Ophthalmol Vis Sci. 2016 Aug 1;57(10):4347-55. doi: 10.1167/iovs.16-19725. PMID: 27556218
19. Modulation of wound healing in glaucoma surgery. Van de Velde S, Van Bergen T, Vandewalle E, Moons L, Stalmans I. Prog Brain Res. 2015;221:319-40. doi: 10.1016/bs.pbr.2015.05.002. Epub 2015 Jun 30. PMID: 26518085 Review.
20. Rho kinase inhibitor AMA0526 improves surgical outcome in a rabbit model of glaucoma filtration surgery. Van de Velde S, Van Bergen T, Vandewalle E, Kindt N, Castermans K, Moons L, Stalmans I. Prog Brain Res. 2015;220:283-97. doi: 10.1016/bs.pbr.2015.04.014. Epub 2015 Jun 30. PMID: 26497796 Review.
21. The Role of LOX and LOXL2 in the Pathogenesis of an Experimental Model of Choroidal Neovascularization. Van Bergen T, Spangler R, Marshall D, Hollanders K, Van de Veire S, Vandewalle E, Moons L, Herman J, Smith V, Stalmans I. Invest Ophthalmol Vis Sci. 2015 Aug;56(9):5280-9. doi: 10.1167/iovs.14-15513. PMID: 26258612
22. Inhibition of Rho-Associated Kinase Prevents Pathological Wound Healing and Neovascularization After Corneal Trauma. Sijnave D, Van Bergen T, Castermans K, Kindt N, Vandewalle E, Stassen JM, Moons L, Stalmans I. Cornea. 2015 Sep;34(9):1120-9. doi: 10.1097/ICO.0000000000000493. PMID: 26075454
23. Complementary effects of bevacizumab and MMC in the improvement of surgical outcome after glaucoma filtration surgery. Van Bergen T, Vandewalle E, Moons L, Stalmans I. Acta Ophthalmol. 2015 Nov;93(7):667-78. doi: 10.1111/aos.12766. Epub 2015 May 18. PMID: 25988844
24. Early diagnosis and successful treatment of paraneoplastic melanocytic proliferation. Jansen JC, Van Calster J, Pulido JS, Miles SL, Vile RG, Van Bergen T, Cassiman C, Spielberg LH, Leys AM. Br J Ophthalmol. 2015 Jul;99(7):943-8. doi: 10.1136/bjophthalmol-2014-305893. Epub 2015 Apr 23. PMID: 25908835 Free PMC article.
25. The effect of AMA0428, a novel and potent ROCK inhibitor, in a model of neovascular age-related macular degeneration. Hollanders K, Van Bergen T, Kindt N, Castermans K, Leysen D, Vandewalle E, Moons L, Stalmans I. Invest Ophthalmol Vis Sci. 2015 Jan 27;56(2):1335-48. doi: 10.1167/iovs.14-15681. PMID: 25626969
26. Bevacizumab revisited: its use in different mouse models of ocular pathologies. Hollanders K, Van Bergen T, Van de Velde S, Sijnave D, Vandewalle E, Moons L, Stalmans I. Curr Eye Res. 2015 May;40(6):611-21. doi: 10.3109/02713683.2014.943910. Epub 2014 Aug 12. PMID: 25117905
27. Improving patient outcomes following glaucoma surgery: state of the art and future perspectives. Van Bergen T, Van de Velde S, Vandewalle E, Moons L, Stalmans I. Clin Ophthalmol. 2014 May 2;8:857-67. doi: 10.2147/OPTH.S48745. eCollection 2014. PMID: 24833892 Free PMC article. Review.
28. AMA0076, a novel, locally acting Rho kinase inhibitor, potently lowers intraocular pressure in New Zealand white rabbits with minimal hyperemia. Van de Velde S, Van Bergen T, Sijnave D, Hollanders K, Castermans K, Defert O, Leysen D, Vandewalle E, Moons L, Stalmans I. Invest Ophthalmol Vis Sci. 2014 Feb 18;55(2):1006-16. doi: 10.1167/iovs.13-13157. PMID: 24474276
29. Intracameral bevacizumab as an adjunct to trabeculectomy: a 1-year prospective, randomised study. Vandewalle E, Abegão Pinto L, Van Bergen T, Spielberg L, Fieuws S, Moons L, Spileers W, Zeyen T, Stalmans I. Br J Ophthalmol. 2014 Jan;98(1):73-8. doi: 10.1136/bjophthalmol-2013-303966. Epub 2013 Oct 24. PMID: 24158846 Clinical Trial.
30. Inhibition of placental growth factor improves surgical outcome of glaucoma surgery. Van Bergen T, Jonckx B, Hollanders K, Sijnave D, Van de Velde S, Vandewalle E, Moons L, Stassen JM, Stalmans I. J Cell Mol Med. 2013 Dec;17(12):1632-43. doi: 10.1111/jcmm.12151. Epub 2013 Oct 9. PMID: 24118824 Free PMC article
31. The role of LOX and LOXL2 in scar formation after glaucoma surgery. Van Bergen T, Marshall D, Van de Veire S, Vandewalle E, Moons L, Herman J, Smith V, Stalmans I. Invest Ophthalmol Vis Sci. 2013 Aug 27;54(8):5788-96. doi: 10.1167/iovs.13-11696. PMID: 23821193
32. The role of different VEGF isoforms in scar formation after glaucoma filtration surgery. Van Bergen T, Vandewalle E, Van de Veire S, Dewerchin M, Stassen JM, Moons L, Stalmans I. Exp Eye Res. 2011 Nov;93(5):689-99. doi: 10.1016/j.exer.2011.08.016. Epub 2011 Sep 1. PMID: 21907194
33. The effect of bevacizumab on human Tenon fibroblasts in ocular wound healing. Van Bergen T, Stalmans I. Invest Ophthalmol Vis Sci. 2010 Dec;51(12):6903-4; author reply 6904. doi: 10.1167/iovs.10-6116. PMID: 21123794 No abstract available.
34. Further pharmacological and genetic evidence for the efficacy of PlGF inhibition in cancer and eye disease. Van de Veire S, Stalmans I, Heindryckx F, Oura H, Tijeras-Raballand A, Schmidt T, Loges S, Albrecht I, Jonckx B, Vinckier S, Van Steenkiste C, Tugues S, Rolny C, De Mol M, Dettori D, Hainaud P, Coenegrachts L, Contreres JO, Van Bergen T, Cuervo H, Xiao WH, Le Henaff C, Buysschaert I, Kharabi Masouleh B, Geerts A, Schomber T, Bonnin P, Lambert V, Haustraete J, Zacchigna S, Rakic JM, Jiménez W, Noël A, Giacca M, Colle I, Foidart JM, Tobelem G, Morales-Ruiz M, Vilar J, Maxwell P, Vinores SA, Carmeliet G, Dewerchin M, Claesson-Welsh L, Dupuy E, Van Vlierberghe H, Christofori G, Mazzone M, Detmar M, Collen D, Carmeliet P. Cell. 2010 Apr 2;141(1):178-90. doi: 10.1016/j.cell.2010.02.039. PMID: 20371353
35. Inhibition of vascular endothelial growth factor reduces scar formation after glaucoma filtration surgery. Li Z, Van Bergen T, Van de Veire S, Van de Vel I, Moreau H, Dewerchin M, Maudgal PC, Zeyen T, Spileers W, Moons L, Stalmans I. Invest Ophthalmol Vis Sci. 2009 Nov;50(11):5217-25. doi: 10.1167/iovs.08-2662. Epub 2009 May 27. PMID: 19474408